Arterial Vascular Pruning, Right Ventricular Size, and Clinical Outcomes in Chronic Obstructive Pulmonary Disease. A Longitudinal Observational Study

Washko GR, Nardelli P, Ash SY, Sanchez-Ferrero GV, Rahaghi FN, Come CE, Dransfield MT, Kalhan R, Han MK, Bhatt SP, et al. Arterial Vascular Pruning, Right Ventricular Size, and Clinical Outcomes in Chronic Obstructive Pulmonary Disease. A Longitudinal Observational Study. Am J Respir Crit Care Med. 2019;200(4):454–461.

Abstract

Cor pulmonale (right ventricular [RV] dilation) and cor pulmonale parvus (RV shrinkage) are both described in chronic obstructive pulmonary disease (COPD). The identification of emphysema as a shared risk factor suggests that additional disease characterization is needed to understand these widely divergent cardiac processes. To explore the relationship between computed tomography measures of emphysema and distal pulmonary arterial morphology with RV volume, and their association with exercise capacity and mortality in ever-smokers with COPD enrolled in the COPDGene Study. Epicardial (myocardium and chamber) RV volume (RV), distal pulmonary arterial blood vessel volume (arterial BV5: vessels
Last updated on 02/26/2023