Pulmonary Arterial Pruning Is Associated With CT-Derived Bronchiectasis Progression in Smokers

Dolliver WR, Wang W, Nardelli P, Rahaghi FN, Orejas JL, Maselli DJ, Yen A, Young K, Kinney G, epar RSJ e E, et al. Pulmonary Arterial Pruning Is Associated With CT-Derived Bronchiectasis Progression in Smokers. Respir Med. 2022;202:106971.

Abstract

Loss of small pulmonary arteries measured as the ratio of blood vessel volume in arteries <5 mm2 in cross-section to total arterial blood vessel volume (BV5a/TBVa), with lower values indicating more pruning, was associated with 5-yr progressing CT-derived bronchiectasis in smokers (Odds Ratio (OR) [95% Confidence interval], 1.28 [1.07-1.53] per 5% lower BV5a/TBVa, P = 0.007). Corresponding results in smokers with COPD were: OR 1.45 [1.11-1.89] per 5% lower BV5a/TBVa, P = 0.007. The results support a vascular factor for structural progression of bronchiectasis.
Last updated on 02/26/2023