The association of white matter free water with cognition in older adults

Gullett JM, O\textquoterightShea A, Lamb DG, Porges EC, O\textquoterightShea DM, Pasternak O, Cohen RA, Woods AJ. The association of white matter free water with cognition in older adults. Neuroimage. 2020;219:117040.

Abstract

BACKGROUND: Extracellular free water within cerebral white matter tissue has been shown to increase with age and pathology, yet the cognitive consequences of free water in typical aging prior to the development of neurodegenerative disease remains unclear. Understanding the contribution of free water to cognitive function in older adults may provide important insight into the neural mechanisms of the cognitive aging process.
Last updated on 02/26/2023