Uehara-Aoyama K, Nakamura M, Asami T, Yoshida T, Hayano F, Roppongi T, Fujiwara A, Inoue T, Shenton ME, Hirayasu Y. Sexually dimorphic distribution of orbitofrontal sulcogyral pattern in schizophrenia. Psychiatry Clin Neurosci. 2011;65(5):483–9.
Abstract
AIM: The sulcogyral pattern of the orbitofrontal cortex (OFC) is characterized by a remarkable inter-individual variability that likely reflects neurobehavioral traits and genetic aspects of neurodevelopment. The aim of the present study was to evaluate the OFC sulcogyral pattern of patients with schizophrenia (SZ) and healthy controls (HC) to determine group differences in OFC sulcogyral pattern as well as gender differences between groups. METHODS: Forty-seven SZ patients (M/F, 23/24) and forty-seven HC (M/F, 17/30), matched on age and gender, were analyzed using magnetic resonance imaging. The sulcogyral pattern was classified into type I, II, or III based on the guidelines set by Chiavaras and Petrides in a previous paper. Chi-squared analysis was used to investigate group and gender differences in the sulcogyral pattern distribution, and categorical regression was used to explore clinical correlations.
Last updated on 02/26/2023