MR diffusion is sensitive to mechanical loading in human intervertebral disks ex vivo.

Alkalay RN, Burstein D, Westin C-F, Meier D, Hackney DB. MR diffusion is sensitive to mechanical loading in human intervertebral disks ex vivo.. J Magn Reson Imaging. 2015;41(3):654–64.

Abstract

PURPOSE: To use T2 and diffusion MR to determine the change in the mechanical function of human disks with increased degenerative state. MATERIALS AND METHODS: Spatial changes in T2 and diffusion were quantified in five cadaveric human lumbar disks under compressive loads. Regression models were used to investigate the relationship between the change in MR parameters and the disk’s dynamic and viscoelastic properties.
Last updated on 02/26/2023