Evidence for reduced cerebellar volumes in trichotillomania.

Keuthen NJ, Makris N, Schlerf JE, Martis B, Savage CR, McMullin K, Seidman LJ, Schmahmann JD, Kennedy DN, Hodge SM, et al. Evidence for reduced cerebellar volumes in trichotillomania. Biol Psychiatry. 2007;61(3):374–81.

Abstract

BACKGROUND: Limited knowledge exists regarding the neurobiology of trichotillomania (TTM). Cerebellum (CBM) volumes were explored, given its role in complex, coordinated motor sequences. METHODS: Morphometric magnetic resonance imaging (MRI) scans were obtained for 14 female subjects with DSM-IV diagnoses of TTM and 12 age-, education-, and gender-matched normal control (NC) participants. Parcellation was performed utilizing a recently developed methodology to measure subterritory volumes of the CBM. Regions were defined based on knowledge of the structural and functional subunits of the CBM.
Last updated on 02/26/2023