Diaz AA, Han MK, Come CE, epar R ul SJ e E, Ross JC, Kim V, Dransfield MT, Curran-Everett D, Schroeder JD, Lynch DA, et al. Effect of emphysema on CT scan measures of airway dimensions in smokers. Chest. 2013;143(3):687–93.
Abstract
BACKGROUND: In CT scans of smokers with COPD, the subsegmental airway wall area percent (WA%) is greater and more strongly correlated with FEV1 % predicted than WA% obtained in the segmental airways. Because emphysema is linked to loss of airway tethering and may limit airway expansion, increases in WA% may be related to emphysema and not solely to remodeling. We aimed to first determine whether the stronger association of subsegmental vs segmental WA% with FEV1 % predicted is mitigated by emphysema and, second, to assess the relationships among emphysema, WA%, and total bronchial area (TBA).
Last updated on 02/26/2023