In Vivo Visualization of White Matter Fiber Tracts of Preterm- and Term- Infant Brain with Diffusion Tensor MRI

S.-S. Yoo, H. J. Park, J. S. Soul, H. Mamata, C.-F. Westin, H. Bassan, A. J. Du Plessis, R. L. Robertson, S. A. Ringer, S. E. Maier, J. J. Volpe, G. P. Zientara
Investigative Radiology
Volume 40, Number 2, Pages 110-115
February, 2005

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Abstract

The goal of this study was to test the feasibility of visualizing a 3-dimensional structure of cerebral white matter fiber tracts in preterm infants, postconceptional age (PCA) 28 weeks to term, by using volumetric diffusion tensor magnetic resonance imaging (DTI) data.

Three-dimensional rendering of the traced white matter tracts for different connectivity in the brain (data obtained from a fullterm infant). Visualized tracts were embedded with color codes, which represent the magnitude of fractional anisotropy: (A) the genu of corpus callosum, (B) splenium of corpus callosum, and (C) corticospinal tracts (corona radiata). Tractography of (D) optic radiation and (E) inferior fronto-occipital fasciculus are shown overlaid on T2-weighted axial anatomic images.

Reference

Yoo SS, Park HJ, Soul JS, Mamata H, Westin CF, Bassan H, Du Plessis AJ, Robertson RL, Ringer SA, Maier SE, Volpe JJ, Zientara GP. In vivo visualization of white matter fiber tracts of preterm- and term- infant brain with diffusion tensor MRI. Investigative Radiology 2005;40(2):110-115.

Bibtex entry

@Article{yooInvestRad05,
  author         = {S.-S. Yoo and H. J. Park and J. S. Soul and H. Mamata  and 
                   C.-F. Westin and H. Bassan and A. J.  {Du Plessis} and R. L.
                   Robertson and S. A. Ringer and  S. E. Maier and J. J. Volpe 
                   and G. P. Zientara},                                        
  title          = {In Vivo Visualization of White Matter Fiber Tracts of      
                   Preterm- and Term- Infant Brain with Diffusion Tensor       
                   {MRI}},                                                     
  journal        = {Investigative Radiology},                                  
  year           = {2005},                                                     
  volume         = {40},                                                       
  number         = {2},                                                        
  pages          = {110--115},                                                 
  month          = {February}
}                                                

Grants

KMST2004-55-02038, NIH R03-HD041376, NIH P01-NS38475, NIH R01-NS39335

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